The Supplement Stack

Science-backed optimization for brain health. Tested over 30 years. Proven results.

I've tested hundreds of supplements. I've watched what works and what doesn't. I've seen families spend thousands on products that do nothing, and I've seen single supplements change lives.

This page is my curated collection — the supplements that actually deliver results, backed by research, and integrated into the CALM Home Protocol.

Choose Your Path

🧠 Boomer Bio-Hacker
Personal Optimization

"Recharging the Batteries and Clearing the Rust"

You're 50+, noticing cognitive slips, and want to stay sharp. You're beta-testing the future.

The CMA Stack Promise:

29% cognitive improvement in 84 days with physical increases in hippocampal volume and cortical thickness.

👨‍👩‍👧 CALM Home Protocol
Environmental + Metabolic

"Environmental Metabolic Architecture"

Your loved one has been diagnosed with dementia. You're optimizing their environment and metabolism.

The Integration:

CMA stack + specialty supplements + environmental design = comprehensive support.

👨‍👩‍👦 Silver Path
Family Education

"Empowering Families with Proof"

Formal diagnosis. Skeptical family. You need a framework that makes sense.

The Approach:

The House Analogy: new generator + cleaning crew = brain that works better.

🧠 Boomer Bio-Hacker

The CMA Stack: The 29% Cognitive Improvement Protocol

The CMA stack is currently being fast-tracked into a branded prescription drug (potentially called CMA2). Why? Because in Phase II trials, participants achieved a 29% cognitive improvement in just 84 days. MRI scans showed physical increases in hippocampal volume and cortical thickness.

You're not taking a supplement. You're installing a new generator and hiring a full-time cleaning crew for your brain.

The Bio-Hacker Dosing Protocol

ComponentDaily TargetAM DosePM DosePurpose
NR1g500mg500mgNAD+ Energy/Repair
L-Serine12.35g6.17g6.17gCognitive Support/Sleep
NAC2.55g1.27g1.27gAntioxidant/Glutathione
L-Carnitine3.73g1.86g1.86gMitochondrial Oxidation

💡 Pro-Tip:

If NR causes insomnia, move the full 1g dose to the morning.

The Components

1. NR (Nicotinamide Riboside) — 500mg x2 daily
  • ✓ Boosts NAD+ production (the energy currency of your cells)
  • ✓ Supports DNA repair and cellular resilience

The gold standard, clinically tested

2. L-Serine — 6.17g x2 daily
  • ✓ Cognitive support and memory consolidation
  • ✓ Sleep maintenance (3g before bed is a standalone protocol)

Pure, affordable, high-quality

3. NAC (N-Acetyl Cysteine) — 1.27g x2 daily
  • ✓ Antioxidant powerhouse
  • ✓ Supports glutathione production (your body's master antioxidant)
  • ⚠️ Sensory note: NAC has a distinct sulfur smell. If sensitive, use capsules instead of powder

Trusted brand, clean formulation

4. L-Carnitine — 1.86g x2 daily
  • ✓ Mitochondrial fuel oxidation (turns fat into energy)
  • ✓ Supports cellular energy production

Pure, no additives

Elite Lab Targets (Proof of Concept)

Bio-hackers should target:

  • Homocysteine: 6.0–9.0 µmol/L (lower is better; high homocysteine = brain shrinkage)
  • GGT: 10–20 U/L (proves your body is efficiently handling energy metabolism)

👨‍👩‍👧 CALM Home Protocol

"Environmental Metabolic Architecture"

Your loved one has been diagnosed with dementia or mild cognitive impairment. You're not just managing decline — you're optimizing their environment and metabolism to slow it.

The CALM Home Protocol integrates the CMA stack into your home as a behavioral rhythm, not just a pill schedule.

Specialty Supplements for CALM Home

Neuralli® MP (PS128 Psychobiotic)

Supports gut-brain axis regulation through the L. plantarum PS128 strain — a clinically-studied psychobiotic that influences mood, anxiety, and emotional resilience.

  • Who it's for: Dementia patients with anxiety or mood instability
  • Dosing: 1 capsule daily (follow label)
Accentrate® Omega 110 (Phospholipid Omega-3s)

Delivers EPA and DHA in phospholipid form — 6x more brain bioavailable than standard triglyceride fish oil.

  • Why it matters: Your brain is 60% fat. DHA is the primary structural component of brain cell membranes.
  • Dosing: Follow label (typically 1-2 capsules daily)

👨‍👩‍👦 Silver Path

"Empowering Families with Proof"

Your loved one has a formal dementia diagnosis. The family is skeptical. They've tried things that didn't work. They're exhausted and defensive.

The Silver Path uses the "House Analogy" to reduce emotional labor and increase understanding.

The House Analogy

"Think of the brain like a house."

As we age, two things happen:

  1. 1. The power grid flickers — Mitochondria (the energy factories in brain cells) start failing. The brain can't generate enough ATP (cellular energy). Everything slows down: memory, mood, movement.
  2. 2. The trash stops getting picked up — Oxidative stress accumulates. Damaged proteins pile up. Inflammation spreads. The brain's cleanup crew (antioxidant systems) can't keep up.

The CMA stack is like installing a brand-new generator and hiring a full-time cleaning crew.

  • NR + L-Carnitine = New generator (more ATP production)
  • NAC + L-Serine = Cleaning crew (antioxidants + cellular repair)

That's why the memory comes back. That's why mood stabilizes. That's why sleep improves.

Safety Assurance: The COVID-19 Evidence

The CMA stack was tested on COVID-19 patients recovering from severe illness (which damages mitochondria severely). Results:

  • ✓ Patients recovered 3.5 days faster than controls
  • ✓ Cognitive recovery was significantly better
  • ✓ No adverse events

This proves the stack's ability to fix cellular damage rapidly — even in the most damaged brains.

Ready to Optimize?

Join the CALM Home community where caregivers and bio-hackers share their protocols, lab results, and real wins.